May 12, 2017 12:05 PM

Study Reveals THC Reduces Age-Related Memory Loss in Mice

Aside from providing consumers with a psychedelic euphoria, tetrahydrocannabinol (THC) also appears to reverse the age-related decline in memory and learning in old mice, a new cannabis study found earlier this year.

The journal Nature Medicine has recently published a study conducted by Andras Bilkei-Gorzo and his colleagues at the University of Bonn, Germany. The research investigated how chronic use of THC impacted the cognitive abilities of mice.

The researchers carried out tests with three groups of mice aged two months, 12 months, and 18 months. During the study, the mice were implanted with mini-pumps that released either low doses of THC or placebo solution.

After a period of 28 days, the lab mice performed memory and learning tests. The findings showed that the cannabis-treated mature and old mice had the same results as the untreated young mice, while young mice who were treated with THC performed tests less well. The thing is, when the scientists stimulated the brain of young mice with THC, it was an overdrive for their undeveloped systems.

7 Popular Myths About THC
7 Popular Myths About THC
​THC is the most well-known compound of cannabis. However, it has been surrounded by myths and rumors for a long time. A great amount of them is supported by traditionalists and older relatives. Our myth busters will help you recognize propaganda and expose seven most common myths about THC.

In one of the tests, the mice were given a choice of interacting with another mouse or an object. The mouse was more interesting to them, and they spent most of the testing time with the animal. When the test was repeated on another day with the choice of two mice, the already known one and a new one, the mice who remembered the animal they met before spent more time with a new mouse.

However, those mice who had problems with memory and learning spent equal time with the two rodents. The untreated young animals had no problems with distinguishing the new mouse, as well as mature and old mice that improved their cognitive abilities with the help of THC.

When studying the brain system involved in the aging process, the scientists used THC as a cannabis chemical compound that interacts with the endocannabinoid system. This brain's system is responsible for learning, memory, and sensations, like pain. The aging process results in the reduction of the activity of the endocannabinoid system, but THC can restore it to the normal level, according to the researchers.

What Are Marijuana Effects on Your Memory?
What Are Marijuana Effects on Your Memory?
In today's society, cannabis consumers are often perceived as absent-minded and forgetful persons. But how often do you actually have difficulties recalling something after smoking a pipe?

The scientists were impressed with the beneficial effects of THC on age-related memory loss and are going to conduct a human study based on 100 volunteers aged 60 to 70 later this year. Perhaps, starting smoking cannabis at this age will help people prevent problems with cognitive abilities.

However, Dr. Doug Brown, Director of Research at Alzheimer’s Society, told The Independent that the study did not reveal how THC impacted people with dementia, as it focused only on mice and their age-related memory loss. Moreover, the study did not investigate the effects of other cannabinoids that also might impact the endocannabinoid system.

Study Review: 4 Ways Marijuana Could Help for Alzheimer's
Study Review: 4 Ways Marijuana Could Help for Alzheimer's
Every year, on Sept. 21, we celebrate World Alzheimer's Day, a day dedicated to the achievements of medical research that could one day better the lives of millions of people affected by the disease
Similar news
10 Weed Studies of 2016 That Show Medical Benefits of Cannabis
If you want to be aware of the latest scientific findings in the medical benefits of cannabis, MJWellness has collected the top 10 marijuana-related studies released in 2016 that exemplify the healing properties of the herb.
Aug 15, 2016 9:45 AM
5 Ways You Can Benefit From Cannabichromene (CBC)
You may have never heard of cannabichromene (CBC) until now, but you will be surprised at how beneficial this cannabis compound is for your health. While THC gets its popularity due to its psychoactive effect, and CBD is well-known for its anti-convulsant properties, CBC can also provide you with amazing medical benefits.
Jul 28, 2016 9:25 AM
7 Incredible Effects of Smoking Marijuana
With the legalization of cannabis in several American states, scientists now have the opportunity to discover the surprising effects of weed on the human body. Below are some of the benefits of marijuana use for our health.
Jul 10, 2016 9:30 AM